Homografts and the bone bank.

نویسنده

  • J J HERBERT
چکیده

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Transplantation immunity in bone homografting.

The knowledge that homografts of many tissues have a limited period of survival, and the revival of the theory of tissue immunity (Gibson and Medawar 1943, Medawar 1944, 1945) makes it of interest to know how bone homografts compare with other tissues in this respect. Since 1878 homografts ofbone have been known to be clinically effective (Macewen 1912), and the introduction of the bone bank (I...

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Studies in the Transplantation

The introduction of the bone bank in 1942 by Incl#{225}n,and particularly the use of freezedried bone (Kreuz, Hyatt, Turner and Bassett 1951) has been followed by encouraging clinical reports of the method (Carr and Hyatt 1955; Berkin, Yeoman, Williamson, Zinnemann and Dexter 1957). However, it is the experience of most orthopaedic surgeons that, although there is a place for the stored bone gr...

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The effect of frozen irradiated bone homografts on the healing of defects in the mandible and femur of the rat.

Numerous studies have been carried out to determine the effect of various types of bone transplants on the healing pattern of experimentally produced defects in animals (Maatz, Lentz and Graf 1954; Burwell 1963; Heipel, Chase and Herndon 1963; Melcher and Irving 1963; Buring and Urist 1967; Raina 1968). These have repeatedly shown that autogenous bone grafts are better than homogenous and heter...

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Studies in the transplantation of bone. V. The capacity of fresh and treated homografts of bone to evoke transplantation immunity. 1963.

Skin transplanted as a homograft from one animal to a genetically dissimilar animal of the same species is rejected after nine to twelve days, probably because of actively acquired immune reactions (Medawar 1944, 1945; Billingham, Brent and Medawar 1954; Billingham, Brent, Medawar and Sparrow 1954). The acquired resistance is termed either transplantation immunity (Billingham, Brent and Medawar...

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From Penicillin-Streptomycin to Amikacin-Vancomycin: Antibiotic Decontamination of Cardiovascular Homografts in Singapore

BACKGROUND In February 2012, the National Cardiovascular Homograft Bank (NCHB) became the first tissue bank outside of North America to receive accreditation from the American Association of Tissue Banks. From 2008 to 2009, NCHB had been decontaminating its cardiovascular homografts with penicillin and streptomycin. The antibiotic decontamination protocol was changed in January 2010 as amikacin...

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عنوان ژورنال:
  • The Journal of bone and joint surgery. British volume

دوره 33-B 3  شماره 

صفحات  -

تاریخ انتشار 1951